By Tzvi Tzfira,Vitaly Citovsky
Agrobacterium is a plant pathogen which explanations the “crown-gall” ailment, a neoplastic development that effects from the move of a well-defined DNA phase (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host phone, its integration into the host genome, and the expression of oncogenes contained at the T-DNA. The molecular equipment, wanted for T-DNA new release and delivery into the host phone and encoded by way of a sequence of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the topic of diverse experiences during the last a number of many years. at the present time, Agrobacterium is the instrument of selection for plant genetic engineering with an ever increasing host variety that comes with many commercially very important vegetation, plant life, and tree species. in addition, its contemporary software for the genetic transformation of non-plant species, from yeast to cultivated mushrooms or even to human cells, can provide this bacterium a special position sooner or later of biotechnological functions.
The booklet is a finished quantity describing Agrobacterium's biology, interactions with host species, and makes use of for genetic engineering.
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Agrobacterium: From Biology to Biotechnology by Tzvi Tzfira,Vitaly Citovsky